Utah’s Uinta Basin contains one of the largest oil shale resources in the United States. This book examines many of the issues surrounding oil shale development in the Uinta Basin. Focusing on research conducted by investigators associated with The University of Utah’s Institute for Clean and Secure Energy (ICSE), the chapters in this book build on each other across a range of scales and of disciplines to present a comprehensive picture of the opportunities and challenges facing this nascent industry. Scales range from the molecular analysis of kerogen to the basin-scale analysis of oil shale geology. Legal, policy, geologic, chemical, economic, and engineering perspectives provide insight into the nature of the Uinta Basin oil shale resource and the potential costs (both financial and environmental) of its extraction. This book integrates the various analyses in two ways. First, the Skyline 16 oil shale core, which was drilled in the Uinta Basin as part of this research, was the source of samples for much of the work that is discussed in this book. Second, the latter chapters of this book incorporate models and data from the earlier chapters to (1) produce a suite of in situ simulation scenarios that study the effect of well arrangement on energy ratio and (2) evaluate costs and air quality issues associated with these scenarios.